Hollyoaks: Let Loose was a spin-off of Hollyoaks that aired between September and December 2005. The series followed Ben Davies and Lisa Hunter as they decided to leave Hollyoaks for a new life abroad, however, their relationship is put to the test over Lisa's jealousy. The series aired a total of 14 episodes. The series was initially commissioned for 15 episodes, but episode 3 was cancelled suddenly.

• Gemma Atkinson
• Marcus Patric
• Louise Marwood
• Alaistair Southey
• Alex Falk